Familial Tetra-Amelia Syndrome

Tetra-Amelia Syndrome

A newborn was noticed lying unattended in the hospital campus. It had complete absence of all four limbs, deformed ears, facial cleft, proptosis, hydrocephalus, corneal opacity, absent nipples, anterior abdominal wall defect with exstrophy bladder, absent external genitalia, and sacral spina bifida (Fig.1 A & B). The child died after few hours due to aspiration pneumonitis. These features are p...

Tetra-amelia and lung hypo/aplasia syndrome: new case report and review.

Tetra-amelia is a rare malformation that may be associated with other anomalies and is usually inherited in an autosomal recessive pattern. We describe a fetus, born to a nonconsanguineous couple, with tetra-amelia, bilateral cleft lip and palate and bilateral lung agenesis, without other anomalies. Karyotype was normal (46,XX) and premature centromere separation was excluded. No mutation was i...

Anesthetic management of a patient with tetra-amelia.

The case presented is that of a parturient with tetra-amelia, the congenital absence or near absence of all limbs. The difficulties encountered with monitoring and venous access due to absence of extremities illustrate the necessity for a detailed management plan with emphasis on early intervention. The reasons for the high incidence of operative delivery are outlined.

Amelia

Amelia was built by Real World Interface (RWI) using Xavier-a mobile robot platform developed at CMU on a B24 base from RWI-as a prototype. Amelia has substantial engineering improvements over Xavier. Amelia is built on a B21 base. It has a top speed of 32 inches per second, while improved integral dead-reckoning insures extremely accurate drive and position controls. The battery life is six ho...

Amelia